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A unique, functional food that helps to fight the “Cellular Aging Process” by providing the essential nutrients necessary for the protection, repair and revitalization of the body at a cellular level.
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Dr. Mark Smith
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Science |
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VIDACELL™ is
the trademark of ingredients
containing a unique functional
and cellular food formulation
of nutrients that are
essential for bodily
functions. VIDACELL™ contains
all of these naturally
derived nutrients in
a bioavailable form:
- Polysaccharide -
Available as biological
fuel for cellular energy
- Polypeptide - Amino
Acids available in
the right quantity
and ratios to be used
as raw materials to
the cells to perform
their functions effectively
and promote cellular
renewal
- Natural Vitamins & Minerals – As
raw materials for
cellular enzyme production
and overall function
- Phytonutrients – provide
cofactors for cellular
processes
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VIDACELL™ Ultra
Structure |
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Studies
by: Solid State Cross
Polarization Magnetic
Angle Spinning (CP/MAS)
C-NMR (Nuclear Magnetic
Resonance) Spectroscopy.
Mechanically
Hydrolyzed Polysaccharides
and Peptides
VIDACELL™ is
a biologic phytocompound.
It can be classified
as a non-dialyzable high
molecular weight polysaccharide
with low molecular weight
poly-peptides.
The
molecular weights of
the different compounds
range from 150 to 300kDa.
A major chemical feature
of these Polysaccharides
and Peptides is the presence
of linkage of D-glucose
units in the main chain. |
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VIDACELL™ Under
Scanning Electron Microscopy
(SEM) |
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Fig.
1 Atypical Molecular
Pyramid-like
Structure, average size
200-300 microns with
one-sided fiber-like
surface |
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Safety
Report
VIDACELL™ is
hypoallergenic and has
no known side effects.
It contains no dairy,
wheat, sugar, chemicals,
fillers, binders, artificial
colors, artificial flavors,
additives, or preservatives
and it contains no genetically
modified organisms (non-GMO). |
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In-Vitro
Study |
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In-Vitro
Alzheimer Model Study
with Neuroblastoma Cells
(Sawatsri et al.)
Conclusions
and Discussion: In-Vitro
studies of neuroblastoma
(neuron cells) showed
100% cell death and
severe damage of dendrites
when neurotoxins were
induced. However, when
the neuroblastoma (neuron
cells) were pretreated
with the VIDACELL™,
in-vitro studies showed
different levels of
cell survival and apparent
recovery of dendrites
from the neurotoxin
injuries within 48
hours. VIDACELL™ has
a role for intervention
in AD.
Figure: Serving dependent of VIDACELL™ against glutamate-induced toxicity to cells and dendrites, A. LA-N-5 under control conditions appear healthy (cytoplasm and neuronal processes). B. LA-N-5 exposed to 0.2 mM Glutamate after 24 h. display shrunken cell bodies and degeneration of neuronal process. C. LA-N-5 grow in the presence of 0.066 mg/ml VIDACELL™ for 2 days prior to exposure to 0.2 mM Glutamate after 24 h display exhibit clear features of neuronal viability for cell bodies and clearly defined neuronal process similar to those of control neurons not treated with 0.2 mM Glutamate. D. similar C but if increased serving VIDACELL™ to 6.66 mg/ml, showed neuronal viability and neuronal process obviously similar with control (C compare B, D compare B). X 400 |
Conducted
By:
Royal
Thai Army Medical Center,
PMK Research Center and,
Emory University School
of Medicine, Atlanta,
Georgia; USA
Medical
Doctors and Scientific
Advisors:
Researcher:
Col. Sayan Sawatsri,
M.D.; Clinical Associate
Professor of Gynecology
and Obstetrics, Emory
University School of
Medicine, Atlanta, GA,
USA. Director of the
Div. of Family Planning
OB-GYN Dept.; Pharamongkutklao
Hospital and College
of Medicine, Bangkok,
Thailand
Advisors:
Wanphen Yumkhunthong,
M.Sc. Prof. Neil Sidell,
Ph.D., Somchai Boonchuen,
DVM, Dipl. Functional
Medicine, Col. Chalermporn
Boonsiri, M.D. and Col.
Nirundorn Pidet, M.D. |
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In-Vitro
Study |
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In-Vitro
Mitochondria Cellular
Viability/Energy Study
(Sawatsri et al.)
Conclusions
and Discussion: VIDACELL™ showed
dose dependent for
neuroprotective effect
in AD model and 1:100 VIDACELL™ demonstrated
the optimal effect
with a significant
increase of ATP in
mitochondria metabolism
of about 54% when compared
with control. VIDACELL™ has
a role for intervention
in AD.
Conducted
By:
Royal
Thai Army Medical Center,
PMK Research Center and,
Emory University School
of Medicine, Atlanta,
Georgia; USA
Medical
Doctors and Scientific
Advisors:
Researcher:
Col. Sayan Sawatsri,
M.D.; Clinical Associate
Professor of Gynecology
and Obstetrics, Emory
University School of
Medicine, Atlanta, GA,
USA. Director of the
Div. of Family Planning
OB-GYN Dept.; Pharamongkutklao
Hospital and College
of Medicine, Bangkok,
Thailand
Advisors:
Wanphen Yumkhunthong,
M.Sc. Prof. Neil Sidell,
Ph.D., Somchai Boonchuen,
DVM, Dipl. Functional
Medicine, Col. Chalermporn
Boonsiri, M.D. and Col.
Nirundorn Pidet, M.D. |
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Full
Research In-Vitro Study: |
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Neuroprotective
Effect of PSP02 in
Cell Line Models
of Alzheimer’s
disease
(In particular the ATP production in mitochondria metabolism) |
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Colorimetric MTT (Tetrazolium) Assay |
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* p < 0.05 Figure 1. |
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Neuroprotective
effect of 0.033, 0.066,
and 0.33 mg/ml a-PSP02
(1:1000, 1:500, 1:100x)
on LA-N5 that was induced
by a 20 min. exposure
to 30 µM H2O2 (hydrogen
peroxide-induced toxicity).
The highest percentage
of cells viability was
54.5% as estimated by
colorimetric MTT (Tetrazolium)
Assay. The values represent
mean + SEM of at least
three separate experiments,
each performed in triplicate,
p < 0.05 compared
with control group.
Statistical
analysis: Data
was analyzed using
Student’s t test
for measuring the cells
viability of experimental
groups compared with
control groups.
Discussion: The
percentage of cells viability
of neuroblastoma cell
at 0.33 mg/ml of a-PSP02
increased 54% as shown
in Figure 1. A Student’s
t-test (two-tailed) was
used to determine p-value
of the experiment and
showed that p-value was
less than 0.05 (p < 0.05).
It was found that the
percentage of cells viability
at 0.33 mg/ml a-PSP02
(experimental group)
and a control group were
significantly different.
From the result it was
shown that 0.33 mg/ml
a-PSP02 can significantly
survive from hydrogen
peroxide-induced toxicity
when compared with control
group.
Conclusion: a-PSP02
showed dose dependent
for neuroprotective effect
in AD model and 1:100
PSP02 demonstrated the
optimal effect with a
significant increase
of ATP in mitochondria
metabolism of about 54%
when compared with control.
a-PSP02 has a role to
intervention in AD. |
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References: |
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RD, Chen S, Montoya
M, Hsish D, Minaya
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D, Behl C, Lely R, Brack
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G, et al. Mercury induces
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MB, Nielsen SE, Berg
K. Re-examination and
further development of
a precise and rapid dye
method for measuring
cell growth/cell kill.
J. Immunol Meth 1989;
119: 203-10.
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*
These statements have not been
evaluated by the Food & Drug
Administration. This product
is not intended to diagnose,
treat, cure or prevent any
disease. |
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